eIF3H / EIF3S3 antibody [N2C3]
Not tested in other applications.
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||40 kDa (note)
|Positive Controls||293T , A431 , H1299 , HeLaS3 , HepG2 , Molt-4 , Raji|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||eukaryotic translation initiation factor 3, subunit H|
|Product Description||Rabbit polyclonal antibody to EIF3S3 (eukaryotic translation initiation factor 3, subunit H)|
|Background||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.|
|Synonyms||EIF3S3 antibody, MGC102958 antibody, eIF3-gamma antibody, eIF3-p40 antibody, EIF3H antibody, eukaryotic translation initiation factor 3 subunit 3 antibody, eIF-3-gamma antibody, eukaryotic translation initiation factor 3 subunit H antibody, "eukaryotic translation initiation factor 3, subunit 3 gamma, 40kDa antibody", "eukaryotic translation initiation factor 3, subunit 3 (gamma, 40kD) antibody", "eukaryotic translation initiation factor 3, subunit 2 (beta, 36kD) antibody", eIF3 p40 subunit antibody, "eukaryotic translation initiation factor 3, subunit H antibody"|
|Cellular Localization||Cytoplasm |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human EIF3 gamma. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Chicken, Bovine|
|Predict Reactivity Note||Mouse (96%), Rat (97%), Chicken (90%), Bovine (97%)|