FEN1 antibody [4E7]
|Full Name||flap structure-specific endonuclease 1|
|Synonyms||RAD2, P39748, FEN-1, 600393, MF1, FEN1, 2237, FEN 1|
|Product Description||Mouse monoclonal [4E7] FEN1|
|Background||FEN-1 (Flap Endonuclease and Five prime Exonuclease) is a 42 a protein that functions as an endonuclease that cleaves branched DNA structures containing single-stranded 5' flaps or as an exonuclease on DNA nicks and gaps. FEN-1 endonuclease and exonuclease activities are stimulated by an association with proliferating cell nuclear antigen (PCNA) in the nucleus. FEN-1 is believed to have important roles in DNA replication and repair and is required in cell-free DNA replication systems. |
|Immunogen||Recombinant human FEN-1 protein encoding amino acids 1-380 purified E. coli.|
|Species Reactivity||Human, Mouse|
|Applications||ICC/IF, IP, WB|
Not tested in other applications.
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||42|
|Purification||Protein G Affinity Purified|
|Purification Note||From hybridoma tissue culture supernatant|
|Storage Buffer||Phosphate-buffered saline, pH 7.4, containing no preservatives |
|Storage Instruction||Keep as concentrated solution. Store at 4°C short term. For extended storage aliquot and store at -20°C or below. Avoid freeze-thaw cycles.|
|Notes||For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not suitable for human or animal consumption.|