|Full Name||crystallin, gamma C|
|Product Description||Rabbit polyclonal antibody to Gamma-crystallin C (crystallin, gamma C)|
|Background||Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Gamma-crystallins are a homogeneous group of highly symmetrical, monomeric proteins typically lacking connecting peptides and terminal extensions. They are differentially regulated after early development. Four gamma-crystallin genes (gamma-A through gamma-D) and three pseudogenes (gamma-E, gamma-F, gamma-G) are tandemly organized in a genomic segment as a gene cluster. Whether due to aging or mutations in specific genes, gamma-crystallins have been involved in cataract formation. [provided by RefSeq]|
|Synonyms||CCL antibody, CRYG3 antibody, CRYGC antibody, gamma-crystallin 2-1 antibody, "crystallin, gamma-3 antibody", gamma-crystallin C antibody, gamma-C-crystallin antibody, gamma-crystallin 3 antibody, "crystallin, gamma C antibody"|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human gamma C Crystallin. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Dog, Rhesus Monkey, Chimpanzee, Bovine, Guinea pig|
|Predict Reactivity Note||Mouse (84%), Rat (85%), Dog (87%), Rhesus Monkey (96%), Chimpanzee (99%), Bovine (85%), Guinea pig (86%)|