|Full Name||RAD23 homolog B (S. cerevisiae)|
|Product Description||Rabbit Polyclonal antibody to hHR23b (RAD23 homolog B (S. cerevisiae))|
|Background||The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in the nucleotide excision repair (NER). This protein was found to be a component of the protein complex that specifically complements the NER defect of xeroderma pigmentosum group C (XP-c) cell extracts in vitro. This protein was also shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, and thus this protein may be involved in the ubiquitin mediated proteolytic pathway in cells. [provided by RefSeq]|
|Synonyms||HHR23B antibody, HR23B antibody, P58 antibody, RAD23B antibody, XP-C repair complementing protein antibody, XP-C repair complementing complex 58 kDa antibody, UV excision repair protein RAD23 homolog B antibody, XP-C repair-complementing complex 58 kDa protein antibody, "RAD23, yeast homolog of, B antibody", RAD23 homolog B (S. cerevisiae) antibody|
|Cellular Localization||Nucleus , Cytoplasm |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human RAD23B. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Rhesus Monkey, Chimpanzee, Bovine|
|Predict Reactivity Note||Mouse (87%), Rat (88%), Rhesus Monkey (98%), Chimpanzee (94%), Bovine (91%)|