hnRNP A2B1 antibody
|Applications||ICC/IF, IHC-P, IP, WB|
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||37 kDa (note)
|Positive Controls||293T , A431 , HeLa , HepG2 , A375 , Neuro2A , GL261 , C8030 , NIH-3T3 , BCL-1 , Raw264.7 , C2C12 , PC-12|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||heterogeneous nuclear ribonucleoprotein A2/B1|
|Product Description||Rabbit Polyclonal antibody to hnRNP A2B1 (heterogeneous nuclear ribonucleoprotein A2/B1)|
|Background||This gene belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. This gene has been described to generate two alternatively spliced transcript variants which encode different isoforms. [provided by RefSeq]|
|Synonyms||DKFZp779B0244 antibody, FLJ22720 antibody, HNRNPA2 antibody, HNRNPB1 antibody, HNRPA2 antibody, HNRPA2B1 antibody, HNRPB1 antibody, RNPA2 antibody, SNRPB1 antibody, HNRNPA2B1 antibody, hnRNP A2 / hnRNP B1 antibody, heterogeneous nuclear ribonucleoproteins A2/B1 antibody, nuclear ribonucleoprotein particle A2 protein antibody, heterogeneous nuclear ribonucleoprotein A2/B1 antibody|
|Cellular Localization||Nucleus , nucleoplasm , Cytoplasm (By similarity) |
|Specificity||Knockdown/Knockout validation was supported by references (PMID:26991015)|
|Validated Note||PMID: 26990993|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human hnRNP A2B1. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rhesus Monkey, Bovine|
|Predict Reactivity Note||Rhesus Monkey (100%), Bovine (100%)|