hnRNP A/B antibody
|Applications||ICC/IF, IHC-P, IP, WB, ChIP-seq|
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
| Immunoprecipitation||Assay-dependent dilution
| ChIP-sequencing||Assay-dependent dilution
Immunoprecipitation : target validated by Mass SpectrometryNot tested in other applications.
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||36 kDa (note)
|Positive Controls||NT2D1 , IMR32 , Jurkat , HeLa|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||heterogeneous nuclear ribonucleoprotein A/B|
|Product Description||Rabbit Polyclonal antibody to hnRNP A/B (heterogeneous nuclear ribonucleoprotein A/B)|
|Background||This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are produced by RNA polymerase II and are components of the heterogeneous nuclear RNA (hnRNA) complexes. They are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene, which binds to one of the components of the multiprotein editosome complex, has two repeats of quasi-RRM (RNA recognition motif) domains that bind to RNAs. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq]|
|Synonyms||ABBP1 antibody, FLJ40338 antibody, HNRPAB antibody, HNRNPAB antibody, hnRNP type A/B protein antibody, "apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1-binding protein 1 antibody", ABBP-1 antibody, heterogeneous nuclear ribonucleoprotein A/B antibody, APOBEC1-binding protein 1 antibody, hnRNP A/B antibody, apobec-1 binding protein 1 antibody|
|Cellular Localization||Nucleus |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human hnRNP A/B. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Xenopus laevis, Pig, Chicken, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Mouse (97%), Rat (97%), Xenopus laevis (90%), Pig (100%), Chicken (92%), Rhesus Monkey (100%), Bovine (98%)|