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hnRNP C1/C2 antibody [4F4]

Cat. No. GTX80388

Reference 1

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 4F4

Isotype

 IgG1

Application

 WB, ICC/IF, IP, ELISA

Reactivity

 Human, Monkey
Package
50 μl ($319)
See all hnRNP C1/C2 products

APPLICATION

Application Note

Recommended Starting Dilutions:
For WB: Use at 1:100,000
Optimal dilutions should be determined experimentally by the researcher.

Calculated MW

34 kDa. ( Note )

Product Note

This antibody recognizes the two hnRNP C proteins of 41kDa (C1) and 43kDa (C2) in human cells, and the corresponding proteins in monkey hamster & chicken. Does cross react with mouse in IP, but not IB

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.1% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Immunogen

RNP’s eluted from oligo (dT) cellulose column

Purification

Protein A

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

heterogeneous nuclear ribonucleoprotein C (C1/C2) , C1 , C2 , HNRNP , HNRPC , SNRPC

Cellular Localization

Nucleus

Background

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene can act as a tetramer and is involved in the assembly of 40S hnRNP particles. Multiple transcript variants encoding at least two different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]

Database

Research Area

REFERENCE

Clone Reference

Claudio Asencio et al. Life Science Alliance 2018; (Epub) Silica-based solid-phase extraction of cross-linked nucleic acid–bound proteins.
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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 319