hnRNP H antibody [N1C1]
|Applications||ICC/IF, IHC-P, WB|
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||49 kDa (note)
|Positive Controls||A431 , H1299 , HeLa , HepG2 , Raji , NCI-H929 , mouse brain|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||heterogeneous nuclear ribonucleoprotein H1 (H)|
|Product Description||Rabbit Polyclonal antibody to hnRNP H (heterogeneous nuclear ribonucleoprotein H1 (H))|
|Background||This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs. It is very similar to the family member HNRPF. This gene is thought to be potentially involved in hereditary lymphedema type I phenotype. [provided by RefSeq]|
|Synonyms||DKFZp686A15170 antibody, HNRPH antibody, HNRPH1 antibody, hnRNPH antibody, HNRNPH1 antibody, hnRNP H antibody, heterogeneous nuclear ribonucleoprotein H antibody, heterogeneous nuclear ribonucleoprotein H1 (H) antibody|
|Cellular Localization||Nucleus , nucleoplasm |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human hnRNP H. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Xenopus laevis, Chicken, Bovine|
|Predict Reactivity Note||Rat (99%), Xenopus laevis (91%), Chicken (96%), Bovine (100%)|