|Full Name||leucine proline-enriched proteoglycan (leprecan) 1|
|Product Description||Rabbit polyclonal antibody to leprecan 1(Gros1) (leucine proline-enriched proteoglycan (leprecan) 1)|
|Background||This gene encodes an enzyme that is a member of the collagen prolyl hydroxylase family. These enzymes are localized to the endoplasmic reticulum and their activity is required for proper collagen synthesis and assembly. Mutations in this gene are associated with osteogenesis imperfecta type VIII. Two alternatively spliced transcript variants encoding different isoforms have been described. Other variants may exist, but their biological validity has not been determined. [provided by RefSeq]|
|Synonyms||GROS1 antibody, MGC117314 antibody, OI8 antibody, P3H1 antibody, LEPRE1 antibody, prolyl 3-hydroxylase 1 antibody, leucine- and proline-enriched proteoglycan 1 antibody, leprecan antibody, growth suppressor 1 antibody, leucine proline-enriched proteoglycan (leprecan) 1 antibody|
|Cellular Localization||Endoplasmic reticulum (By similarity) , Secreted , extracellular space , extracellular matrix (By similarity) |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human leprecan 1(Gros1). The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Human, Mouse, Rat, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Human (100%), Mouse (95%), Rat (95%), Rhesus Monkey (99%), Bovine (95%)|