|Full Name||cholinergic receptor, muscarinic 3|
|Product Description||Rabbit Polyclonal antibody to mAChR M3|
|Background||The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 3 controls smooth muscle contraction and its stimulation causes secretion of glandular tissue. [provided by RefSeq]|
|Synonyms||HM3 antibody, CHRM3 antibody, m3 muscarinic receptor antibody, muscarinic acetylcholine receptor M3 antibody, "cholinergic receptor, muscarinic 3 antibody"|
|Cellular Localization||Cell membrane , Cell junction , synapse , postsynaptic cell membrane , Basolateral cell membrane |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Muscarinic acetylcholine receptor M3. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Pig, Rhesus Monkey, Chimpanzee, Bovine, Guinea pig|
|Predict Reactivity Note||Mouse (86%), Rat (84%), Pig (95%), Rhesus Monkey (97%), Chimpanzee (100%), Bovine (92%), Guinea pig (84%)|