|Full Name||transmembrane protein 67|
|Product Description||Rabbit polyclonal antibody to Meckelin (transmembrane protein 67)|
|Background||The protein encoded by this gene localizes to the primary cilium and to the plasma membrane. The gene functions in centriole migration to the apical membrane and formation of the primary cilium. Multiple transcript variants encoding different isoforms have been found for this gene. Defects in this gene are a cause of Meckel syndrome type 3 (MKS3) and Joubert syndrome type 6 (JBTS6). [provided by RefSeq]|
|Synonyms||JBTS6 antibody, MECKELIN antibody, MGC26979 antibody, MKS3 antibody, NPHP11 antibody, TNEM67 antibody, TMEM67 antibody, meckel syndrome type 3 protein antibody, transmembrane protein 67 antibody|
|Cellular Localization||Cell membrane; Multi-pass membrane protein |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human meckelin isoform 1. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Bovine|
|Predict Reactivity Note||Mouse (82%), Rat (81%), Bovine (88%)|