nm23-H1 antibody [N1C3]
Not tested in other applications.
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||17 kDa (note)
|Positive Controls||293T , H1299 , HeLa , HepG2 , Molt-4 , Raji , mouse brain|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||non-metastatic cells 1, protein (NM23A) expressed in|
|Product Description||Rabbit Polyclonal antibody to nm23-H1 (non-metastatic cells 1, protein (NM23A) expressed in)|
|Background||This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. [provided by RefSeq]|
|Synonyms||AWD antibody, GAAD antibody, NB antibody, NBS antibody, NDKA antibody, NDPK-A antibody, NDPKA antibody, NM23 antibody, NM23-H1 antibody, NME1 antibody, metastasis inhibition factor nm23 antibody, nucleoside diphosphate kinase A antibody, granzyme A-activated DNase antibody, NDP kinase A antibody, tumor metastatic process-associated protein antibody, "non-metastatic cells 1, protein (NM23A) expressed in antibody"|
|Cellular Localization||Cytoplasm , Nucleus |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human nm23-H1. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Dog, Pig, Rabbit, Chicken, Rhesus Monkey, Chimpanzee, Bovine, Guinea pig|
|Predict Reactivity Note||Rat (95%), Dog (92%), Pig (95%), Rabbit (92%), Chicken (84%), Rhesus Monkey (98%), Chimpanzee (100%), Bovine (94%), Guinea pig (92%)|