| Full Name | S-phase kinase-associated protein 1 |
| Product Description | Mouse monoclonal [3G222] to SKP1 |
| Background | Skp1 is an F-box protein which functions as a substrate recognition component of the SCF ubiquitin ligase complex. It binds to cyclin F, S-phase kinase-associated protein 2, and other regulatory proteins involved in ubiquitin proteolysis through an F-box motif. It is also involved in the control of beta-catenin levels the activity of beta-catenin dependent TCF transcription factors. Studies have also characterized the protein as an RNA polymerase II elongation factor. |
| Synonyms | EMC19, MGC34403, OCP-II, OCP2, SKP1A, TCEB1L, p19A, OCP II, OCPII |
| Specificity | Recognizes human SKP1 (p19) protein at 19kD |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone Name | 3G222 |
| Target | SKP1 |
| Isotype | IgG1 |
| Immunogen | Recombinant human SKP1 (p19) protein |
| Antigen Species | Human |
| Species Reactivity | Human |