Full Name | S-phase kinase-associated protein 1 |
Background | Skp1 is an F-box protein which functions as a substrate recognition component of the SCF ubiquitin ligase complex. It binds to cyclin F, S-phase kinase-associated protein 2, and other regulatory proteins involved in ubiquitin proteolysis through an F-box motif. It is also involved in the control of beta-catenin levels the activity of beta-catenin dependent TCF transcription factors. Studies have also characterized the protein as an RNA polymerase II elongation factor. |
Synonyms | EMC19, MGC34403, OCP-II, OCP2, SKP1A, TCEB1L, p19A, OCP II, OCPII |
Specificity | Recognizes human SKP1 (p19) protein at 19kD |
Host | Mouse |
Clonality | Monoclonal |
Clone Name | 3G222 |
Isotype | IgG1 |
Immunogen | Recombinant human SKP1 (p19) protein |
Antigen Species | Human |
Species Reactivity | Human |
Conjugation | Unconjugated |