|Full Name||ubiquitin B|
|Product Description||Rabbit Polyclonal antibody to ubiquitin B (ubiquitin B)|
|Background||This gene encodes ubiquitin, one of the most conserved proteins known. Ubiquitin is required for ATP-dependent, nonlysosomal intracellular protein degradation of abnormal proteins and normal proteins with a rapid turnover. Ubiquitin is covalently bound to proteins to be degraded, and presumably labels these proteins for degradation. Ubiquitin also binds to histone H2A in actively transcribed regions but does not cause histone H2A degradation, suggesting that ubiquitin is also involved in regulation of gene expression. This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. Aberrant form of this protein has been noticed in patients with Alzheimer's and Down syndrome. [provided by RefSeq]|
|Synonyms||FLJ25987 antibody, MGC8385 antibody, RPS27A antibody, UBA52 antibody, UBC antibody, UBB antibody, polyubiquitin B antibody, polyubiquitin-B antibody, ubiquitin B antibody|
|Cellular Localization||Cytoplasm , Nucleus |
|Immunogen||Full length human ubiquitin B Recombinant protein.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Zebrafish, Pig, Chicken, Sheep, Rhesus Monkey, Chimpanzee, Bovine|
|Predict Reactivity Note||Mouse (99%), Rat (99%), Zebrafish (99%), Pig (100%), Chicken (99%), Sheep (100%), Rhesus Monkey (100%), Chimpanzee (100%), Bovine (99%)|