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5-HT2A receptor antibody

Anti-5-HT2A receptor antibody used in Western Blot (WB). GTX37799
Anti-5-HT2A receptor antibody used in IHC (Paraffin sections) (IHC-P). GTX37799
Anti-5-HT2A receptor antibody used in Flow cytometry (FACS). GTX37799
Anti-5-HT2A receptor antibody used in IHC (Paraffin sections) (IHC-P). GTX37799
Anti-5-HT2A receptor antibody used in IHC (Frozen sections) (IHC-Fr). GTX37799

Cat. No. GTX37799

Reference 4

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, IHC-Fr, FACS

Reactivity

 Human, Mouse, Rat
Package
100 μg ($399)
See all 5-HT2A receptor products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-2000
IHC-P 1:400-800
IHC-Fr Assay dependent
FACS 3μg/Test
Not tested in other applications.

Calculated MW

53 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

0.01M TBS, 0.5% BSA, 25% Glycerol

Preservative

0.015% ProClin 300

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH conjugated synthetic peptide derived from human 5HT2A Receptor (65-160/471AA).

Purification

Protein A purified

Conjugation

Unconjugated

RRID

AB_11162751

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

5-hydroxytryptamine receptor 2A , 5-HT2A , HTR2

Cellular Localization

Cell membrane,Cell projection, dendrite,Cytoplasmic vesicle

Background

This gene encodes one of the receptors for serotonin, a neurotransmitter with many roles. Mutations in this gene are associated with susceptibility to schizophrenia and obsessive-compulsive disorder, and are also associated with response to the antidepressant citalopram in patients with major depressive disorder (MDD). MDD patients who also have a mutation in intron 2 of this gene show a significantly reduced response to citalopram as this antidepressant downregulates expression of this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]

Database

Research Area

DATA IMAGES

Anti-5-HT2A receptor antibody used in Western Blot (WB). GTX37799

GTX37799 WB Image

WB analysis of U251 and BV2 cell lysates using GTX37799 5-HT2A receptor antibody.

Anti-5-HT2A receptor antibody used in IHC (Paraffin sections) (IHC-P). GTX37799

GTX37799 IHC-P Image

IHC-P analysis of rat stomach tissue using GTX37799 5-HT2A receptor antibody.

Anti-5-HT2A receptor antibody used in Flow cytometry (FACS). GTX37799

GTX37799 FACS Image

FACS analysis of U-2OS cells using GTX37799 5-HT2A receptor antibody.

Anti-5-HT2A receptor antibody used in IHC (Paraffin sections) (IHC-P). GTX37799

GTX37799 IHC-P Image

IHC-P analysis of rat brain tissue using GTX37799 5-HT2A receptor antibody.

Anti-5-HT2A receptor antibody used in IHC (Frozen sections) (IHC-Fr). GTX37799

GTX37799 IHC-Fr Image

IHC-Fr analysis of rat brain tissue using GTX37799 5-HT2A receptor antibody.

REFERENCE

Application Reference

Owaki T et al. Dis Model Mech 2022; 15 (7) Involvement of the liver-gut peripheral neural axis in nonalcoholic fatty liver disease pathologies via hepatic HTR2A.
Liu M et al. Biomed Pharmacother 2019; 115 : 108900 Antidepressant-like effects of ginseng fruit saponin in myocardial infarction mice.
Application : WB
Reactivity : Mouse
Pei-Hsin Shie et al. International Immunopharmacology 2016; 31 : 186–194 4,7-Dimethoxy-5-methyl-1,3-benzodioxole from Antrodia camphorata inhibits LPS-induced inflammation via suppression of NF-κB and induction HO-1 in RAW264.7 cells.
Application : WB
Reactivity : Rat
Jihua Fu et al. Int J Biol Sci 2016; 12 (2) : 219-234 Long-term Stress with Hyperglucocorticoidemia-induced Hepatic Steatosis with VLDL Overproduction Is Dependent on both 5-HT2 Receptor and 5-HT Synthesis in Liver.
Application : WB
Reactivity : Rat
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SDS
Glycerol.pdf
Proclin.pdf
Package List Price ($)
$ 399