GeneTex
United States (US)

ABCC11 antibody [MRP8 7C12/4]

Cat No. GTX40220

Host Mouse
Clonality Monoclonal
Clone Name MRP8 7C12/4
Isotype IgM
Application WB, FACS, ELISA
Reactivity Human
APPLICATION

Application Note

ELISA: Use at an assay dependent dilution. FACS: Use at an assay dependent dilution. WB: Use at an assay dependent dilution. Detects a band of approximately 8 kDa. Optimal dilutions/concentrations should be determined by the end user.

Calculated MW

154 kDa. ( Note )

Positive Control

Neutrophil lysate (particularly neutrophils from spleen).
PROPERTIES

Form

Liquid

Buffer

Preservative: None. Constituents: PBS

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

recombinant Human MRP8

Purification

IgG fraction

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Atp Binding Cassette Subfamily C Member 11,Ewwd,Mrp8,Ww,Abcc11

Background

MRP-8 and MRP-14 are cytosolic calcium-binding proteins of 8kDa and 14kDa that form a heterodimer. MRP-8 and MRP-14 are expressed in peripheral blood monocytes, neutrophils and keratinocytes (mature). Expression is lost on tissue maturation of monocytes to macrophages. MRP-14 may be associated with monocyte and neutrophil activation and the accumulation of these cells in inflammatory sites.

Database

Package List Price ($)
$ 319