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ADAM8 antibody

Anti-ADAM8 antibody used in Western Blot (WB). GTX22475
Anti-ADAM8 antibody used in Western Blot (WB). GTX22475

Cat. No. GTX22475

Host

 Goat

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB

Reactivity

 Human
Package
50 μg ($399)
See all ADAM8 products

APPLICATION

Application Note

Western Blot - Approx 90kDa band seen in Human Brain lysate. Recommended for use at 1.0-3.0ug/ml.

Calculated MW

89 kDa. ( Note )

Positive Control

Human Brain lysate.

PROPERTIES

Form

Liquid

Buffer

TBS, 0.5% BSA

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic peptide: QRKQGAGAPTAP, corresponding to C terminal amino acids 813-824 of ADAM8.

Purification

IgG fraction
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

ADAM metallopeptidase domain 8 , CD156 , CD156a , MS2

Cellular Localization

Membrane; Single-pass type I membrane protein

Background

This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene may be involved in cell adhesion during neurodegeneration, and it is thought to be a target for allergic respiratory diseases, including asthma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2009]

Database

Research Area

DATA IMAGES

Anti-ADAM8 antibody used in Western Blot (WB). GTX22475

GTX22475 WB Image

Anti-ADAM8 antibody used in Western Blot (WB). GTX22475

GTX22475 WB Image

Western blot analysis of MS2 (ADAM8, CD156) in human bone marrow lysate using GTX22475 at 1 ug/ ml.

REFERENCE

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REVIEW

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Package List Price ($)
$ 399