APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 2 - 4 μg/ml |
Not tested in other applications.
Calculated MW
Predict Reactivity
Mouse, Rat, Bovine, Dog, Hamster, Chicken, Pig, Bat, Elephant, Gibbon, Gorilla, Horse, Lizard, Marmoset, Opossum, Panda, Turkey(>80% identity)
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.1% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Synthetic 16 amino acid peptide from C-terminus of human ADAMTS5.
Purification
Purified by affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
ADAM metallopeptidase with thrombospondin type 1 motif 5 , ADAMTS 11 , ADAMTS 5 , ADAMTS11 , ADAMTS5 , ADMP2
Cellular Localization
Secreted,Extracellular space,Extracellular matrix
Background
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme contains two C-terminal TS motifs and functions as an aggrecanase that cleaves aggrecan, a major proteoglycan of cartilage, and may mediate cartilage destruction in osteoarthritis. [provided by RefSeq, Feb 2016]
Database
Research Area
DATA IMAGES
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GTX13976 IHC-P Image
IHC-P analysis of human lung, non-small cell carcinoma tissue using GTX13976 ADAMTS5 antibody.
Antigen retrieval : Heat-induced antigen retrieval
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GTX13976 IHC-P Image
IHC-P analysis of human breast, carcinoma tissue using GTX13976 ADAMTS5 antibody.
Antigen retrieval : Heat-induced antigen retrieval
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GTX13976 IHC-P Image
IHC-P analysis of human cartilage tissue using GTX13976 ADAMTS5 antibody.
Antigen retrieval : Heat-induced antigen retrieval
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REFERENCE
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REVIEW
There are currently no reviews for ADAMTS5 antibody (GTX13976). Be the first to share your experience with this product.
