APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
1:1000 |
1:50-1:100 |
1:10-1:50 |
Not tested in other applications.
Calculated MW
Predict Reactivity
Mouse(>80% identity)
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.09% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
KLH conjugated synthetic peptide between 176-205 amino acids from the Central region of human ALDH18A1.
Purification
Protein A purified, followed by peptide affinity purification.
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
aldehyde dehydrogenase 18 family member A1 , ADCL3 , ARCL3A , GSAS , P5CS , PYCS , SPG9 , SPG9A , SPG9B
Cellular Localization
Mitochondrion inner membrane
Background
This gene is a member of the aldehyde dehydrogenase family and encodes a bifunctional ATP- and NADPH-dependent mitochondrial enzyme with both gamma-glutamyl kinase and gamma-glutamyl phosphate reductase activities. The encoded protein catalyzes the reduction of glutamate to delta1-pyrroline-5-carboxylate, a critical step in the de novo biosynthesis of proline, ornithine and arginine. Mutations in this gene lead to hyperammonemia, hypoornithinemia, hypocitrullinemia, hypoargininemia and hypoprolinemia and may be associated with neurodegeneration, cataracts and connective tissue diseases. Alternatively spliced transcript variants, encoding different isoforms, have been described for this gene. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
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GTX80929 WB Image
WB analysis of K562 cell lysate (35ug/lane) using GTX80929 ALDH18A1 antibody, Internal.
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GTX80929 FACS Image
FACS analysis of K562 cells using GTX80929 ALDH18A1 antibody, Internal. Top histogram : negative control Bottom histogram : K562 cells
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GTX80929 IHC-P Image
IHC-P analysis of human brain tissue using GTX80929 ALDH18A1 antibody, Internal.
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REFERENCE
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REVIEW
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