GeneTex
United States (US)

ARC peptide

Cat No. GTX28371

Application Blocking
Species Human
APPLICATION

Application Note

The peptide is used for blocking the activity of GTX22002. Incubatingthe peptide with equal volume of antibody for 30 min at 37ºC usually completely blocks theantibody activity in Western blotting.
PROPERTIES

Form

Liquid

Buffer

PBS pH7.2 with 10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl, 0.1% bovine serum albumin, and 0.02% sodium azide

Storage

Store the peptide at -20˚C, stable for one year.

Concentration

0.20 mg/ml (Please refer to the vial label for the specific concentration.)

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Background

Nucleolar protein 30 (Nop30) is coded by the Arc gene. The nuclear isoform of Nop30 (1/Nop30)may be involved in RNA splicing and the cytoplasmic isoform (2/Myp) may inhibit apoptosis. Isoform 1 oligomerizes and binds to SFRS9/SRp30C and also interacts with NPM1. Isoform 2 binds caspase 2, caspase 8 and CED3 and inhibits caspase 8 activity. Nop30 isoform 1 is found in nucleoli and nucleoplasm. Nop30 isoform 2 is cytoplasmic. Nop30 is highly expressed in heart and skeletal muscle with lower levels detected in placenta, liver, kidney and pancreas

Research Area

Package List Price ($)
$ 179