GeneTex
United States (US)

ARID1A antibody

Cat No. GTX12388

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, ICC/IF, IHC-P
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB Assay dependent
ICC/IF Assay dependent
IHC-P Assay dependent
Not tested in other applications.

Calculated MW

242 kDa kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

5% BSA, 0.9% NaCl, 0.2% Na2HPO4, 0.05% Thimerosal, 0.05% NaN3.

Concentration

0.50mg/ml

Antigen Species

Human

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminal of human ARID1A, identical to the related mouse and rat sequences.

Purification

Immunogen affinity purified.

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

BAF250 Antibody, AT rich interactive domain 1A (SWI-like) Antibody, B120 Antibody, P270 Antibody, SMARCF1 Antibody, hELD Antibody, ELD Antibody, C1orf4 Antibody, hOSA1 Antibody, OSA1 Antibody, BAF250a Antibody, MRD14 Antibody, BM029 Antibody

Background

This gene encodes a member of the SWI/SNF family, whose members have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. It possesses at least two conserved domains that could be important for its function. First, it has a DNA-binding domain that can specifically bind an AT-rich DNA sequence known to be recognized by a SNF/SWI complex at the beta-globin locus. Second, the C-terminus of the protein can stimulate glucocorticoid receptor-dependent transcriptional activation. It is thought that the protein encoded by this gene confers specificity to the SNF/SWI complex and may recruit the complex to its targets through either protein-DNA or protein-protein interactions. Two transcript variants encoding different isof
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Database

Research Area