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AVPR1A antibody, Internal

Anti-AVPR1A antibody, Internal used in Western Blot (WB). GTX89114
Anti-AVPR1A antibody, Internal used in Western Blot (WB). GTX89114

Cat. No. GTX89114

Reference 4

Host

 Goat

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB

Reactivity

 Human, Mouse, Rat, Lasiopodomys mandarinus
Package
100 μg ($399)
See all AVPR1A products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 0.03-0.1μg/ml
Not tested in other applications.

Calculated MW

47 kDa. ( Note )

Positive Control

The peptide used to generate this antibody is available for purchase (GTX89114-PEP).

Predict Reactivity

Bovine, Dog, Pig(>80% identity)

PROPERTIES

Form

Liquid

Buffer

TBS, 0.5% BSA

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.50 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide with sequence CHPLKTLQQPARRSR, from the internal region of the protein sequence according to NP_000697.1.

Purification

Purified by ammonium sulphate precipitation followed by antigen affinity chromatography

Conjugation

Unconjugated

RRID

AB_10724608

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

arginine vasopressin receptor 1A , AVPR V1a , AVPR1 , V1aR

Cellular Localization

Cell membrane; Multi-pass membrane protein

Background

The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1B, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor mediates cell contraction and proliferation, platelet aggregation, release of coagulation factor and glycogenolysis. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-AVPR1A antibody, Internal used in Western Blot (WB). GTX89114

GTX89114 WB Image

WB analysis of NIH-3T3 lysate using GTX89114 AVPR1A antibody, Internal.
Dilution : 0.03μg/ml
Loading : 35μg protein in RIPA buffer

Anti-AVPR1A antibody, Internal used in Western Blot (WB). GTX89114

GTX89114 WB Image

The data was published in the journal Elife in 2019.PMID: 31084703

REFERENCE

Application Reference

Hou W et al. Front Neurosci 2021; 15 : 625116 Sex-Dependent Effects of Chronic Social Defeat on Emotional and Social Behaviors, and Parameters of Oxytocin and Vasopressin Systems in Mandarin Voles (Microtus mandarinus).
Application : WB
Yuan W et al. Neuroendocrinology 2019; (Epub) Preweaning paternal deprivation impacts parental responses to pups and alters the serum OT and CORT levels and OTR, V1AR, ER, D1R, D2R levels in relevant brain regions in adult mandarin voles.
He Z et al. Elife 2019; 8 Increased anxiety and decreased sociability induced by paternal deprivation involve the PVN-PrL OTergic pathway.
He Z et al. bioRxiv 2017; (Epub) Increased anxiety and decreased sociability in adulthood following paternal deprivation involve * in the mPFC.
Application : WB
Reactivity : Mouse
Submit a Reference

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 399