APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 1-2μg/ml for 30 minutes at RT |
|
Note :
IHC-P
Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95ºC followed by cooling at RT for 20 minutes.
|
Not tested in other applications.
Calculated MW
PROPERTIES
Form
Liquid
Buffer
10mM PBS, 0.05% BSA
Preservative
0.05% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
0.2 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Recombinant human ALPL protein
Purification
Protein A/G purified
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
ALPL , APTNAP , HOPS , TNAP , TNSALP , alkaline phosphatase, liver/bone/kidney , Bone Alkaline Phosphatase , Alkaline Phosphatase (Tissue Non-Specific) , alkaline phosphatase, biomineralization associated
Cellular Localization
Cell membrane
Background
This gene encodes a member of the alkaline phosphatase family of proteins. There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature enzyme. This enzyme may play a role in bone mineralization. Mutations in this gene have been linked to hypophosphatasia, a disorder that is characterized by hypercalcemia and skeletal defects. [provided by RefSeq, Oct 2015]
Database
Research Area
DATA IMAGES
![Anti-Alkaline Phosphatase (Tissue Non-Specific) antibody [ALPL/597] used in IHC (Paraffin sections) (IHC-P). GTX34402](/templates/default/js/lightbox/images/loading.gif "Anti-Alkaline Phosphatase (Tissue Non-Specific) antibody [ALPL/597] used in IHC (Paraffin sections) (IHC-P). GTX34402")
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GTX34402 IHC-P Image
IHC-P analysis of human endometrial carcinoma tissue using GTX34402 Alkaline Phosphatase (Tissue Non-Specific) antibody [ALPL/597].
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GTX34402 IHC-P Image
IHC-P analysis of human testicular carcinoma tissue using GTX34402 Alkaline Phosphatase (Tissue Non-Specific) antibody [ALPL/597].
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GTX34402 IHC-P Image
IHC-P analysis of human colon carcinoma tissue using GTX34402 Alkaline Phosphatase (Tissue Non-Specific) antibody [ALPL/597].
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GTX34402 IHC-P Image
IHC-P analysis of human ovarian carcinoma tissue using GTX34402 Alkaline Phosphatase (Tissue Non-Specific) antibody [ALPL/597].
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REFERENCE
There are currently no references for Alkaline Phosphatase (Tissue Non-Specific) antibody [ALPL/597] (GTX34402). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for Alkaline Phosphatase (Tissue Non-Specific) antibody [ALPL/597] (GTX34402). Be the first to share your experience with this product.
![Anti-Alkaline Phosphatase (Tissue Non-Specific) antibody [ALPL/597] used in IHC (Paraffin sections) (IHC-P). GTX34402](/upload/website/prouct_img/small/GTX34402/GTX34402_20200115_IHC-P_530_w_23060801_518.webp "Anti-Alkaline Phosphatase (Tissue Non-Specific) antibody [ALPL/597] used in IHC (Paraffin sections) (IHC-P). GTX34402")
![Anti-Alkaline Phosphatase (Tissue Non-Specific) antibody [ALPL/597] used in IHC (Paraffin sections) (IHC-P). GTX34402](/upload/website/prouct_img/small/GTX34402/GTX34402_20200115_IHC-P_1185_w_23060801_154.webp "Anti-Alkaline Phosphatase (Tissue Non-Specific) antibody [ALPL/597] used in IHC (Paraffin sections) (IHC-P). GTX34402")
![Anti-Alkaline Phosphatase (Tissue Non-Specific) antibody [ALPL/597] used in IHC (Paraffin sections) (IHC-P). GTX34402](/upload/website/prouct_img/small/GTX34402/GTX34402_20200115_IHC-P_442_w_23060801_200.webp "Anti-Alkaline Phosphatase (Tissue Non-Specific) antibody [ALPL/597] used in IHC (Paraffin sections) (IHC-P). GTX34402")
![Anti-Alkaline Phosphatase (Tissue Non-Specific) antibody [ALPL/597] used in IHC (Paraffin sections) (IHC-P). GTX34402](/upload/website/prouct_img/small/GTX34402/GTX34402_20200115_IHC-P_803_w_23060801_473.webp "Anti-Alkaline Phosphatase (Tissue Non-Specific) antibody [ALPL/597] used in IHC (Paraffin sections) (IHC-P). GTX34402")
![Anti-Alkaline Phosphatase (Tissue Non-Specific) antibody [ALPL/597] used in IHC (Paraffin sections) (IHC-P). GTX34402](/upload/website/prouct_img/normal/GTX34402/GTX34402_20200115_IHC-P_530_w_23060801_518.webp "Anti-Alkaline Phosphatase (Tissue Non-Specific) antibody [ALPL/597] used in IHC (Paraffin sections) (IHC-P). GTX34402")
![Anti-Alkaline Phosphatase (Tissue Non-Specific) antibody [ALPL/597] used in IHC (Paraffin sections) (IHC-P). GTX34402](/upload/website/prouct_img/normal/GTX34402/GTX34402_20200115_IHC-P_1185_w_23060801_154.webp "Anti-Alkaline Phosphatase (Tissue Non-Specific) antibody [ALPL/597] used in IHC (Paraffin sections) (IHC-P). GTX34402")
![Anti-Alkaline Phosphatase (Tissue Non-Specific) antibody [ALPL/597] used in IHC (Paraffin sections) (IHC-P). GTX34402](/upload/website/prouct_img/normal/GTX34402/GTX34402_20200115_IHC-P_442_w_23060801_200.webp "Anti-Alkaline Phosphatase (Tissue Non-Specific) antibody [ALPL/597] used in IHC (Paraffin sections) (IHC-P). GTX34402")
![Anti-Alkaline Phosphatase (Tissue Non-Specific) antibody [ALPL/597] used in IHC (Paraffin sections) (IHC-P). GTX34402](/upload/website/prouct_img/normal/GTX34402/GTX34402_20200115_IHC-P_803_w_23060801_473.webp "Anti-Alkaline Phosphatase (Tissue Non-Specific) antibody [ALPL/597] used in IHC (Paraffin sections) (IHC-P). GTX34402")