GeneTex
United States (US)

Apolipoprotein E3 recombinant protein

ApoE3-recombinant-protein_WB_GTX65008-1_18121409_972.jpg

Cat No. GTX65008

Application WB, ELISA, Functional Assay, Apuri, Blocking
Reactivity Human
Species Human
APPLICATION

Calculated MW

34 kDa. ( Note )
PROPERTIES

Form

Lyophilized powder

Buffer

20 mM Sodium Phosphate

Storage

Reconstitute in 5 mM Sodium Phosphate pH 7.8 + 0.5 mM DTT to a concentration of 0.1-1.0 mg/ml. The solution can then be diluted into other aqueous buffers and stored at 4ºC for 1 week or –20ºC for future use.

Antigen Species

Human

Expression System

E. coli

Purification


Purity was assessed by SDS-PAGE (≥90%) and by HPLC (≥90%).

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Apolipoprotein E,Ad2,Apo-E,Apoe4,Ldlcq5,Lpg,Apoe

Background

ApoE belongs to a group of proteins that bind reversibly with lipoprotein and play an important role in lipid metabolism. In addition to facilitating solublization of lipids, these proteins help to maintain the structural integrity of lipoproteins, serve as ligands for lipoprotein receptors, and regulate the activity of enzymes involved in lipid metabolism. Significant quantities of ApoE are produced in liver and brain and to some extent in almost every organ. ApoE is an important constituent of all plasma lipoproteins. It’s interaction with specific ApoE receptor enables uptake of chylomicron remnants by liver cells, which is an essential step during normal lipid metabolism. ApoE exists in three major isoforms; E2, E3, and E4, which differ from one another by a single amino-acid substitution. E3 is the most common isoform and is present in 40-90% of the population. Recombinant human ApoE3 is a 34.0 kDa protein containing 299 amino acid residues. This protein has a N-terminal His-tag.

Research Area

DATA IMAGES
ApoE3-recombinant-protein_WB_GTX65008-1_18121409_972.jpg

GTX65008 WB Image

Western blot analysis of ApoE3 recombinant protein using GTX65008

Package List Price ($)
$ 199