GeneTex
United States (US)

BMP11 recombinant protein

Cat No. GTX65313

Application ELISA, Functional Assay, Apuri, Blocking
Reactivity Human
Species Human
APPLICATION

Application Note

The protein is biologically active as determined by its ability to induce alkaline phosphatase production by C2C12 cells. The ED50 is in the range of 0.4-4 ug/ml.

Calculated MW

32.6 kDa. ( Note )
PROPERTIES

Form

Lyophilized powder

Buffer

10 mM Sodium Citrate, pH 3.5.

Storage

Reconstitute to a concentration of 0.1-1.0 mg/ml in water containing BSA (50 mg BSA per 1 mg of protein). This solution can then be diluted into other aqueous buffers. Stored at -20ºC for future use.

Antigen Species

Human

Expression System

E. coli

Purification


Purity was assessed by SDS-PAGE (≥98%) and by HPLC (≥98%).

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

GDF11, Growth/Differentiation Factor-11, bone morphogenetic protein11, BMP 11, Growth/Differentiation Factor11, GDF 11, BMP11, GDF-11, bone morphogenetic protein 11, BMP11/GDF11

Background

BMPs (bone morphogenetic proteins) belong to the TGF-beta superfamily of structurally related signaling proteins. As implied by their name, BMPs promote and regulate bone development, growth, remodeling and repair, in both prenatal development and postnatal growth of eye, heart, kidney, skin, and other tissues. Recombinant human BMP-11 is N-terminus His-tagged protein with a molecular weight of 32.6 kDa (for homodimeric) and 16.2 (for monomeric) consisting of 136 amino acid polypeptide chains.
Package List Price ($)
$ 369