GeneTex
United States (US)

BMP6 recombinant protein

Cat No. GTX65020

Application ELISA, Functional Assay, Apuri, Blocking
Reactivity Human
Species Human
APPLICATION

Application Note

GeneTex' s recombinant human BMP-6 is biologically active. The ED50 as determined by dose-dependent induction of alkaline phosphatase activity with C2C12 cells is in the range of 2-12 ug/ml.

Calculated MW

monomer (15 kDa), dimer (30 kDa) kDa. ( Note )
PROPERTIES

Form

Lyophilized powder

Storage

Reconstitute to a concentration of 0.1-1.0 mg/ml in sterile 20 mM acetic acid. This solution can then be diluted into other aqueous buffers and stored at 4ºC for 1 week or –20ºC for future use.

Antigen Species

Human

Expression System

E. coli

Purification


Purity was assessed by SDS-PAGE (≥98%) and by HPLC (≥98%).

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

VGR1, BMP-6, BMP6, VGR, BMP 6

Background

BMPs (bone morphogenetic proteins) belong to the TGF-beta superfamily of structurally related signaling proteins. As implied by their name, BMPs promote and regulate bone development, growth, remodeling and repair, in both prenatal development and postnatal growth of eye, heart, kidney, skin, and other tissues. Recombinant human BMP-6 produced from E. coli contains a mixture of monomer (15 kDa), dimer (30 kDa), and multimers. The dimer is an active polypeptide chain containing 2X142 amino acid residues.
Package List Price ($)
$ 249