APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
1:1000 |
Assay dependent |
Not tested in other applications.
Calculated MW
Predict Reactivity
Mouse(>80% identity)
PROPERTIES
Form
Liquid
Buffer
10mM HEPES pH7.5, 150mM Sodium Chloride, 0.1mg/ml BSA, 50% Glycerol
Preservative
No preservative
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Antigen Species
Human
Immunogen
Synthetic phosphopeptide corresponding to residues around Ser180 of human Btk.
Purification
Unpurified
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
AGMX1 , AT , ATK , BPK , BTK , Bruton tyrosine kinase , IMD1 , PSCTK1 , XLA
Cellular Localization
Cytoplasm,Cell membrane,Nucleus
Background
The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2013]
Database
Research Area
DATA IMAGES
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GTX14393 WB Image
WB analysis of extracts from hydrogen peroxide treated or serum starved THP1 cells using GTX14393 BTK (phospho Ser180) antibody [3i5(3D3)].
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REFERENCE
There are currently no references for BTK (phospho Ser180) antibody [3i5(3D3)] (GTX14393). Be the first to share your publications with this product.
REVIEW
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