APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 10 - 15 μg/ml |
Not tested in other applications.
Calculated MW
Predict Reactivity
Bovine, Pig, Gibbon, Gorilla, Horse, Panda(>80% identity)
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.1% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Synthetic 18 amino acid peptide from C-terminus of human BDKRB1.
Purification
Purified by affinity chromatography
Conjugation
Unconjugated
RRID
AB_375366
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
bradykinin receptor B1 , B1BKR , B1R , BDKRB1 , BDKRB2 , BKB1R , BKR1 , BRADYB1 , Bradykinin B1 receptor , Bradykinin receptor B1
Cellular Localization
Cell membrane
Background
Bradykinin, a 9 aa peptide, is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. Two types of G-protein coupled receptors have been found which bind bradykinin and mediate responses to these pathophysiologic conditions. The protein encoded by this gene is one of these receptors and is synthesized de novo following tissue injury. Receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
Database
Research Area
DATA IMAGES
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GTX70845 IHC-P Image
IHC-P analysis of pituitary tissue using GTX70845 Bradykinin B1 receptor antibody.
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GTX70845 IHC-P Image
IHC-P analysis of pituitary tissue using GTX70845 Bradykinin B1 receptor antibody.
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GTX70845 IHC-P Image
IHC-P analysis of human placenta tissue using GTX70845 Bradykinin B1 receptor antibody.
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GTX70845 IHC-P Image
IHC-P analysis of heart, myocardial infarct tissue using GTX70845 Bradykinin B1 receptor antibody.
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GTX70845 IHC-P Image
IHC-P analysis of human nasal mucosa tissue using GTX70845 Bradykinin B1 receptor antibody.
Antigen retrieval : Heat-induced antigen retrieval
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GTX70845 IHC-P Image
IHC-P analysis of human vascular smooth muscle tissue using GTX70845 Bradykinin B1 receptor antibody.
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REFERENCE
REVIEW
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