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C3 / C3a antibody

Anti-C3 / C3a antibody used in Western Blot (WB). GTX78199

Cat. No. GTX78199

Host

 Chicken

Clonality

 Polyclonal

Isotype

 IgY

Application

 WB, ELISA

Reactivity

 Mouse
Package
100 μg ($399)
See all C3 products

APPLICATION

Application Note

This product can be used at 1:2,000 to 1:10,000 for both ELISA and immunoblot testing. User needs to try out the titrations for optimization in assay.

Calculated MW

187 kDa. ( Note )

Product Note

Binds to a stong band at about 9KDa (C3a), two weaker bands with one at about 115KDa (C3 alpha) and the other at 25-36KDa (unknown or partial C3 cleavage.)

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Mouse

Immunogen

Mouse C3 alpha peptide aa 678-692

Purification

Affinity purified with antigen.

Conjugation

Unconjugated

RRID

AB_626119

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

complement C3 , AHUS5 , ARMD9 , ASP , C3a , C3b , CPAMD1 , HEL-S-62p

Cellular Localization

Secreted

Background

Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form the mature protein, which is then further processed to generate numerous peptide products. The C3a peptide, also known as the C3a anaphylatoxin, modulates inflammation and possesses antimicrobial activity. Mutations in this gene are associated with atypical hemolytic uremic syndrome and age-related macular degeneration in human patients. [provided by RefSeq, Nov 2015]

Database

Research Area

DATA IMAGES

Anti-C3 / C3a antibody used in Western Blot (WB). GTX78199

GTX78199 WB Image

Western Blot anaylsis of GTX78199 chicken anti-mouse C3a on mouse serum (1 ul).

REFERENCE

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REVIEW

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SDS
PBS.pdf
Package List Price ($)
$ 399