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CCDC106 antibody

Anti-CCDC106 antibody used in IHC (Paraffin sections) (IHC-P). GTX85167
Anti-CCDC106 antibody used in Western Blot (WB). GTX85167
Anti-CCDC106 antibody used in IHC (Paraffin sections) (IHC-P). GTX85167

Cat. No. GTX85167

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, ELISA

Reactivity

 Human, Mouse, Rat
Package
100 μg ($399)
See all CCDC106 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 0.5 - 1 μg/mL
IHC-P 5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

32 kDa. ( Note )

Positive Control

Human Brain Tissue Lysate(GTX27918)

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

CCDC106 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human CCDC106.The immunogen is located within the last 50 amino acids of CCDC106.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

coiled-coil domain containing 106 , HSU79303 , ZNF581

Cellular Localization

Nucleus

Background

The coiled-coil domain is a common protein motif that is often involved in protein oligomerization and is found in proteins such as transcription factors and intermediate filaments. CCDC106 was initially identified as a p53-interacting protein by yeast two-hybrid screening. Other experiments demonstrated that CCDC106 co-localizes and interacts with p53 in the nucleus, inhibiting the transcriptional activity of p53 and stimulating p53 protein degradation, indicating that at least one of the functions of CCDC106 is acting as a negative regulator of p53.

Database

Research Area

DATA IMAGES

Anti-CCDC106 antibody used in IHC (Paraffin sections) (IHC-P). GTX85167

GTX85167 IHC-P Image

IHC-P analysis of rat brain tissue using GTX85167 CCDC106 antibody.
Working concentration : 20 μg/ml

Anti-CCDC106 antibody used in Western Blot (WB). GTX85167

GTX85167 WB Image

WB analysis of human brain tissue lysate using GTX85167 CCDC106 antibody.
Working concentration : (A) 0.5 and (B) 1 μg/ml

Anti-CCDC106 antibody used in IHC (Paraffin sections) (IHC-P). GTX85167

GTX85167 IHC-P Image

IHC-P analysis of rat brain tissue using GTX85167 CCDC106 antibody.
Working concentration : 5 μg/ml

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399