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CCR8 antibody

Anti-CCR8 antibody used in IHC (Paraffin sections) (IHC-P). GTX78055

Cat. No. GTX78055

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 IHC-P

Reactivity

 Human
Package
25 μg ($299)
See all CCR8 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 28 μg/ml
Not tested in other applications.

Calculated MW

41 kDa. ( Note )

Predict Reactivity

Elephant, Gibbon, Gorilla, Marmoset, Panda(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.1% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic 18 amino acid peptide from N-terminal extracellular domain of human CCR8.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

RRID

AB_425003

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

C-C motif chemokine receptor 8 , CC motif chemokine receptor 8 , CCCKR8 , CCR8 , CDw198 , CKRL1 , CMKBR8 , CMKBRL2 , CY6 , GPRCY6 , TER1 , CD198

Cellular Localization

Cell membrane

Background

This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. This gene is located at the chemokine receptor gene cluster region. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-CCR8 antibody used in IHC (Paraffin sections) (IHC-P). GTX78055

GTX78055 IHC-P Image

IHC-P analysis of human tonsil, germinal center and mantle zone tissue using GTX78055 CCR8 antibody.
Antigen retrieval : Heat-induced antigen retrieval

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 299