PBS with BSA and less than 0.1% sodium azide.
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
Synthetic peptide: DGILFIYGVILTALFLRVK, corresponding to amino acids 36-54 of Human CD3 zeta.
Protein A purified
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
CD3 consists of five invariant polypeptide chains that associate to form three dimmers: a heterodimer of gamma and epsilon chains, a heterodimer of delta and epsilon chains and a homodimer of two zeta chains or a heterodimer of zeta and eta chains. Zeta chain consists of three consecutive copies of the same motif. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response.