GeneTex
United States (US)

CD3 zeta antibody

GTX17061_IHC-P_18121410_330.jpg

Cat No. GTX17061

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application IHC-P
Reactivity Human, Mouse, Rat, Sheep, Pig
APPLICATION

Application Note

IHC-P: 1/50 - 1/100. Perform heat mediated antigen retrieval before commencing with IHC staining protocol with 10 mM Citrate buffer, pH 6.0. Optimal dilutions/concentrations should be determined by the end user.

Calculated MW

19 kDa. ( Note )

Positive Control

Tonsil
PROPERTIES

Form

Liquid

Buffer

PBS with BSA and less than 0.1% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Antigen Species

Human

Immunogen

Synthetic peptide: DGILFIYGVILTALFLRVK, corresponding to amino acids 36-54 of Human CD3 zeta.

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Cd247 Molecule,Cd3-Zeta,Cd3H,Cd3Q,Cd3Z,Imd25,T3Z,Tcrz,Cd247

Cellular Localization

Cell Membrane

Background

CD3 consists of five invariant polypeptide chains that associate to form three dimmers: a heterodimer of gamma and epsilon chains, a heterodimer of delta and epsilon chains and a homodimer of two zeta chains or a heterodimer of zeta and eta chains. Zeta chain consists of three consecutive copies of the same motif. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response.

Database

Research Area

DATA IMAGES
GTX17061_IHC-P_18121410_330.jpg

GTX17061 IHC-P Image

IHC-P analysis of human tonsil stained using CD3 zeta antibody.

Package List Price ($)
$ 329