Sterile filtered and then lyophilized from 10 mM Sodium Phosphate, pH 7.5 + 0.1 M Arginine
Reconstitute in water to a concentration of 0.1-1.0 mg/ml. The solution can then be diluted into other aqueous buffers. Stored at -20ºC for future use.
Purity was assessed by SDS-PAGE (≥98%) and by HPLC (≥98%).
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Tumor necrosis factor ligand superfamily member 5, TRAP, CD40L, IMD3, IGM, TNF-related activation protein, TNFSF5, HIGM1, hCD40L., T cell antigen Gp39, CD40lg, TNFrelated activation protein, TBAM, CD154 antigen, Tumor necrosis factor ligand superfamily member5, CD40-L, sCD40, T-BAM, T BAM, CD40 L, TNF related activation protein
CD40 Ligand (CD40L/TRAP) is a type II transmembrane glycoprotein belonging to the TNF superfamily of ligands. Natually, CD40L is a membrane-bound protein, but proteolytically cleaved 15-18 kDa soluble forms of CD40L are also fully active. CD40L plays an important role in the proliferation and differentiation of B-cells, and is critical for immunoglobulin (Ig) class switching. Recombinant murine CD40 Ligand is a soluble 18 kDa protein containing 149 amino acid residues comprising the receptor binding TNF-like domain of CDE40L.