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CD42b antibody [HIP1]

Anti-CD42b antibody [HIP1] used in Flow cytometry (FACS). GTX22578

Cat. No. GTX22578

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 HIP1

Isotype

 IgG1

Application

 IHC-Fr, FACS

Reactivity

 Human, Primate
Package
100 μg ($399)
See all CD42b products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-Fr Assay dependent
FACS Assay dependent
Not tested in other applications.

Calculated MW

72 kDa. ( Note )

Product Note

This antibody reacts with CD42b (GPIb alpha).

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

15mM Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peripheral blood mononuclear cells of a patient suffering with CLL.

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

BDPLT1 , BDPLT3 , BSS , CD42B , CD42balpha , DBPLT3 , GP1B , GP1BA , GPIbA , GPIbalpha , VWDP , glycoprotein Ib platelet alpha subunit , CD42b , glycoprotein Ib platelet subunit alpha

Cellular Localization

Membrane

Background

Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer, an alpha chain and a beta chain, that is linked by disulfide bonds. The Gp Ib functions as a receptor for von Willebrand factor (VWF). The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and platelet glycoprotein V. The binding of the GP Ib-IX-V complex to VWF facilitates initial platelet adhesion to vascular subendothelium after vascular injury, and also initiates signaling events within the platelet that lead to enhanced platelet activation, thrombosis, and hemostasis. This gene encodes the alpha subunit. Mutations in this gene result in Bernard-Soulier syndromes and platelet-type von Willebrand disease. The coding region of this gene is known to contain a polymophic variable number tandem repeat (VNTR) domain that is associated with susceptibility to nonarteritic anterior ischemic optic neuropathy. [provided by RefSeq, Oct 2013]

Database

Research Area

DATA IMAGES

Anti-CD42b antibody [HIP1] used in Flow cytometry (FACS). GTX22578

GTX22578 FACS Image

FACS analysis of human peripheral blood using GTX22578 CD42b antibody [HIP1].

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399