APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 1:50-1:200 |
Not tested in other applications.
Calculated MW
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
No preservative
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1.07 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
The immunogen used to generate this antibody corresponds to human CD45.
Purification
Affinity purified by Protein G.
Conjugation
Unconjugated
RRID
AB_2888029
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
protein tyrosine phosphatase receptor type C , B220 , CD45 , CD45R , GP180 , L-CA , LCA , LY5 , T200
Cellular Localization
Membrane
Background
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus belongs to receptor type PTP. This gene is specifically expressed in hematopoietic cells. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Four alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq]
Database
Research Area
DATA IMAGES
![Anti-CD45 antibody [GT0005] used in Flow cytometry (FACS). GTX628417](/templates/default/js/lightbox/images/loading.gif "Anti-CD45 antibody [GT0005] used in Flow cytometry (FACS). GTX628417")
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GTX628417 FACS Image
CD45 antibody [GT0005] (GTX628417) detects CD45 protein by flow cytometry analysis.
Sample: THP-1 cell.
Black: Unlabelled sample was used as a control.
Red: CD45 antibody [GT0005] (GTX628417) dilution: 1:50.
Acquisition of 20,000 events were collected for FACS analysis.
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REFERENCE
There are currently no references for CD45 antibody [GT0005] (GTX628417). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for CD45 antibody [GT0005] (GTX628417). Be the first to share your experience with this product.
![Anti-CD45 antibody [GT0005] used in Flow cytometry (FACS). GTX628417](/upload/website/prouct_img/small/GTX628417/GTX628417_42338_20151228_FACS_w_23051500_782.webp "Anti-CD45 antibody [GT0005] used in Flow cytometry (FACS). GTX628417")
![Anti-CD45 antibody [GT0005] used in Flow cytometry (FACS). GTX628417](/upload/website/prouct_img/normal/GTX628417/GTX628417_42338_20151228_FACS_w_23051500_782.webp "Anti-CD45 antibody [GT0005] used in Flow cytometry (FACS). GTX628417")