GeneTex
United States (US)

CLIC4 antibody

GTX30778_1448_WB_18121410_146.jpg
GTX30778_700_IHC-P_18121410_235.jpg

Cat No. GTX30778

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:1000
IHC-P 1:10-1:50
Not tested in other applications.

Calculated MW

29 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS, 0.09% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent(Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

This CLIC4 antibody is generated from rabbits immunized with recombinant human CLIC4 protein.

Purification

Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Intracellular chloride ion channel protein p64H1, p64H1, Chloride intracellular channel 4, CLIC4, Chloride intracellular channel protein 4, Chloride intracellular channel 4 (mitochondrial), Chloride intracellular channel4, HUH1, CLIC4L, H1, Chloride intracellular channel4 (mitochondrial), mtCLIC, Chloride intracellular channel protein4, DKFZP566G223, Chloride intra, FLJ38640

Background

Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 4 (CLIC4) protein, encoded by the CLIC4 gene, is a member of the p64 family; the gene is expressed in many tissues and exhibits a intracellular vesicular pattern in Panc-1 cells (pancreatic cancer cells) (from Entrez Gene). CLIC4 is thought to play a role in apoptosis and has been shown to translocate to the nucleus under stress conditions.

Database

Research Area

DATA IMAGES
GTX30778_1448_WB_18121410_146.jpg

GTX30778 WB Image

WB analysis of 293 cell lysate (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the CLIC4 (Lane 2) using GTX30778 CLIC4 antibody.

GTX30778_700_IHC-P_18121410_235.jpg

GTX30778 IHC-P Image

IHC-P analysis of human breast carcinoma using GTX30778 CLIC4 antibody.