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CRBN antibody

Anti-CRBN antibody used in Western Blot (WB). GTX31611
Anti-CRBN antibody used in IHC (Paraffin sections) (IHC-P). GTX31611
Anti-CRBN antibody used in IHC (Paraffin sections) (IHC-P). GTX31611

Cat. No. GTX31611

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, ELISA

Reactivity

 Human, Mouse, Rat
Package
100 μg ($399)
See all CRBN products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1 - 2 μg/mL
IHC-P 5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

51 kDa. ( Note )

Positive Control

Human Testis Tissue Lysate(GTX15374)

Product Note

At least two isoforms of CRBN are known to exist; this antibody will detect both isoforms.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

CRBN antibody was raised against a 16 amino acid peptide near the carboxy terminus of human CRBN.The immunogen is located within the last 50 amino acids of CRBN.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

cereblon , MRT2 , MRT2A

Cellular Localization

Cytoplasm,Nucleus,Membrane

Background

This gene encodes a protein related to the Lon protease protein family. In rodents and other mammals this gene product is found in the cytoplasm localized with a calcium channel membrane protein, and is thought to play a role in brain development. Mutations in this gene are associated with autosomal recessive nonsyndromic mental retardation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]

Database

Research Area

DATA IMAGES

Anti-CRBN antibody used in Western Blot (WB). GTX31611

GTX31611 WB Image

WB analysis of human testis tissue lysate using GTX31611 CRBN antibody.
Working concentration : (A) 0.5 and (B) 1 μg/ml

Anti-CRBN antibody used in IHC (Paraffin sections) (IHC-P). GTX31611

GTX31611 IHC-P Image

IHC-P analysis of rat testis tissue using GTX31611 CRBN antibody.
Working concentration : 5 μg/ml

Anti-CRBN antibody used in IHC (Paraffin sections) (IHC-P). GTX31611

GTX31611 IHC-P Image

IHC-P analysis of rat testis tissue using GTX31611 CRBN antibody.
Working concentration : 20 μg/ml

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399