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CRISP2 antibody

Anti-CRISP2 antibody used in Western Blot (WB). GTX85002
Anti-CRISP2 antibody used in IHC (Paraffin sections) (IHC-P). GTX85002
Anti-CRISP2 antibody used in IHC (Paraffin sections) (IHC-P). GTX85002

Cat. No. GTX85002

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, ELISA

Reactivity

 Human
Package
100 μg ($399)
See all CRISP2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 0.5 - 1 μg/mL
IHC-P 10 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

27 kDa. ( Note )

Positive Control

Human Testis Tissue Lysate(GTX15374) , Human Testis Tissue Slide(GTX21748)

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

CRISP2 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human CRISP2.The immunogen is located within the first 50 amino acids of CRISP2.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

cysteine rich secretory protein 2 , CRISP-2 , CT36 , GAPDL5 , TPX1 , TSP1

Cellular Localization

Secreted

Background

The cysteine-rich secretory proteins (CRISP) family is a group of four proteins that are strongly expressed in the male reproductive tract and have been implicated in having roles in male fertility. CRISP2, also known as TPX1, has been implicated in the adhesion between spermatids and Sertoli cells, and with CRISP1, is thought to be involved in sperm-egg fusion. CRISP2 has been shown to regulate the Ca2+ influx through ryanodine receptors (RYR) and may influence the acrosome reaction or sperm motility. CRISP2 has also been shown to bind to the mitogen-activated protein kinase kinase kinase 11 (MAP3K11) and localizes to the developing acrosome, suggesting this CRISP2-MAP3K11 complex may have a role in acrosome development.

Database

Research Area

DATA IMAGES

Anti-CRISP2 antibody used in Western Blot (WB). GTX85002

GTX85002 WB Image

WB analysis of human testis tissue lysate using GTX85002 CRISP2 antibody.
Working concentration : (A) 0.5 and (B) 1 μg/ml

Anti-CRISP2 antibody used in IHC (Paraffin sections) (IHC-P). GTX85002

GTX85002 IHC-P Image

IHC-P analysis of human testis tissue using GTX85002 CRISP2 antibody.
Working concentration : 20 μg/ml

Anti-CRISP2 antibody used in IHC (Paraffin sections) (IHC-P). GTX85002

GTX85002 IHC-P Image

IHC-P analysis of human testis tissue using GTX85002 CRISP2 antibody.
Working concentration : 10 μg/ml

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399