GeneTex
United States (US)

CSEN antibody [N1C3]

GTX105901_WB_19011506_811.jpg
GTX105901_39932_WB_M_brain_19011506_870.jpg

Cat No. GTX105901

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB
Reactivity Human, Mouse
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500-1:3000
Not tested in other applications.

Calculated MW

29 kDa. ( Note )

Positive Control

CSEN tansfected 293T cell , mouse brain

Predict Reactivity

Rat, Bovine, Rhesus Monkey(>80% identity)
PROPERTIES

Form

Liquid

Buffer

0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.88mg/ml(Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein encompassing a sequence within the center region of human CSEN. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

CSEN antibody, DREAM antibody, KCHIP3 antibody, MGC18289 antibody, KCNIP3 antibody, kv channel-interacting protein 3 antibody, potassium channel interacting protein 3 antibody, calsenilin antibody, "calsenilin, presenilin-binding protein, EF hand transcription factor antibody", A-type potassium channel modulatory protein 3 antibody, DRE-antagonist modulator antibody, "Kv channel interacting protein 3, calsenilin antibody"

Cellular Localization

Cytoplasm , Cell membrane; Lipid-anchor , Endoplasmic reticulum , Golgi apparatus , Nucleus , Cytoplasm , Cell membrane , Endoplasmic reticulum , Golgi apparatus , Nucleus

Background

This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins, which belong to the recoverin branch of the EF-hand superfamily. Members of this family are small calcium binding proteins containing EF-hand-like domains. They are integral subunit components of native Kv4 channel complexes that may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. The encoded protein also functions as a calcium-regulated transcriptional repressor, and interacts with presenilins. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq]

Database

Research Area

DATA IMAGES
GTX105901_WB_19011506_811.jpg

GTX105901 WB Image

Western Blot analysis of KCNIP3 expression in transfected 293T cell line by KCNIP3 polyclonal antibody.
A: Non-transfected lysate.
B: KCNIP3 transfected lysate.
12% SDS PAGE
GTX105901 diluted at 1:500

GTX105901_39932_WB_M_brain_19011506_870.jpg

GTX105901 WB Image

Sample (50 ug of whole cell lysate)
A: Mouse brain
12% SDS PAGE
GTX105901 diluted at 1:1000

SDS
Glycerol.pdf
Thimerosal.pdf
Package List Price ($)
$ 319
$ 169