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CX3CL1 antibody

Anti-CX3CL1 antibody used in Western Blot (WB). GTX74237
Anti-CX3CL1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX74237

Cat. No. GTX74237

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IP, IHC

Reactivity

 Human, Mouse, Rat
Package
100 μg ($399)
See all CX3CL1 products

APPLICATION

Application Note

For WB: Use at a dilution of 1:1,000 - 1:5,000. For IP: Use at a dilution of 1:300 - 1:800. For IHC: Use at a dilution of 1:100 - 1:500. Optimal dilutions/concentrations should be determined by the researcher.

Calculated MW

42 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.1% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fragment - human CX3CL1 (fractalkine)

Purification

Protein A affinity purified
From polyclonal serum

Conjugation

Unconjugated

RRID

AB_376179

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

C-X3-C motif chemokine ligand 1 , ABCD-3 , C3Xkine , CXC3 , CXC3C , NTN , NTT , SCYD1 , fractalkine , neurotactin

Cellular Localization

Cell membrane

Background

This gene belongs to the CX3C subgroup of chemokines, characterized by the number of amino acids located between the conserved cysteine residues. This is the only member of the CX3C subgroup, which contains three amino acids between cysteine residues, resulting in a Cys-X-X-X-Cys configuration. The encoded protein contains an extended mucin-like stalk with a chemokine domain on top, and exists in both a membrane-anchored form where it acts as a binding molecule, or, in soluble form, as a chemotactic cytokine. The mature form of this protein can be cleaved at the cell surface, yielding different soluble forms that can interact with the G-protein coupled receptor, C-X3-C motif chemokine receptor 1 gene product. This gene plays a role in a wide range of diseases, including cancer, vasculitis, neuropathies, atherosclerosis, inflammatory diseases, and in human immunodeficiency virus infections. [provided by RefSeq, Sep 2017]

Database

Research Area

DATA IMAGES

Anti-CX3CL1 antibody used in Western Blot (WB). GTX74237

GTX74237 WB Image

WB detection of hFractalkine in transfected(1) and untransfected(2) cos-7 cells.

Anti-CX3CL1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX74237

GTX74237 ICC/IF Image

HepG2 cells stained with Rabbit anti Human fractalkine (GTX74237), green; counterstained for tubulin, red and nuclei, blue

REFERENCE

Application Reference

Tiberi A et al. Brain 2024; 147 (1) : 122-134 Reversal of neurological deficits by painless nerve growth factor in a mouse model of Rett syndrome.
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REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 399