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CXCL1 / GRO alpha antibody

Anti-CXCL1 / GRO alpha antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX53966
Anti-CXCL1 / GRO alpha antibody used in Western Blot (WB). GTX53966
Anti-CXCL1 / GRO alpha antibody used in Western Blot (WB). GTX53966

Cat. No. GTX53966

Reference 2

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all CXCL1 / GRO alpha products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
ICC/IF Assay dependent
Not tested in other applications.

Calculated MW

11 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-107 of human CXCL1 (NP_001502.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

RRID

AB_2887827

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

C-X-C motif chemokine ligand 1 , FSP , GRO1 , GROa , MGSA , MGSA-a , NAP-3 , SCYB1

Cellular Localization

Secreted

Background

This antimicrobial gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signals through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils. Aberrant expression of this protein is associated with the growth and progression of certain tumors. A naturally occurring processed form of this protein has increased chemotactic activity. Alternate splicing results in coding and non-coding variants of this gene. A pseudogene of this gene is found on chromosome 4. [provided by RefSeq, Sep 2014]

Database

Research Area

DATA IMAGES

Anti-CXCL1 / GRO alpha antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX53966

GTX53966 ICC/IF Image

ICC/IF analysis of C6 cells using GTX53966 CXCL1 / GRO alpha antibody.
Red : Primary antibody
Blue : DAPI for nuclear staining
Dilution : 1:100

Anti-CXCL1 / GRO alpha antibody used in Western Blot (WB). GTX53966

GTX53966 WB Image

WB analysis of Jurkat cell lysate using GTX53966 CXCL1 / GRO alpha antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-CXCL1 / GRO alpha antibody used in Western Blot (WB). GTX53966

GTX53966 WB Image

WB analysis of DU145 cell lysate using GTX53966 CXCL1 / GRO alpha antibody.
Dilution : 1:1000
Loading : 25μg per lane

REFERENCE

Application Reference

Yen-Yun Wang et al. Cancers (Basel) 2020; 12 (12) Visfatin Enhances Breast Cancer Progression through CXCL1 Induction in Tumor-Associated Macrophages.
Application : WB
Reactivity : Human
Chen L et al. Cell Mol Life Sci 2017; (Epub) Blockage of the NLRP3 inflammasome by MCC950 improves anti-tumor immune responses in head and neck squamous cell carcinoma.
Application : WB
Reactivity : Mouse
Submit a Reference

REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399