CXXC4 antibody, C-term

Cat. No. GTX88280

Host	Goat
Clonality	Polyclonal
Isotype	IgG
Application	IHC-P
Reactivity	Human
Package	100 μg ($399)

See all CXXC4 products

Datasheet
Document

View product citations for antibody GTX88280 on CiteAb

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Recommended Dilution
IHC-P	3-5μg/ml
Note : IHC-P Human Breast shows cystoplasm staining in myoepithelial cells.

Not tested in other applications.

Positive Control

The peptide used to generate this antibody is available for purchase (GTX88280-PEP).

Predict Reactivity

Mouse(>80% identity)

PROPERTIES

Form

Liquid

Buffer

TBS, 0.5% BSA

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.50 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide with sequence C-GTSLERTPVPSAEA, from the C-Terminus (near) of the protein sequence according to NP_079488.1.

Purification

Purified by ammonium sulphate precipitation followed by antigen affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CXXC finger protein 4 , IDAX

Background

This gene encodes a CXXC-type zinc finger domain-containing protein that functions as an antagonist of the canonical wingless/integrated signaling pathway. The encoded protein negatively regulates wingless/integrated signaling through interaction with the post synaptic density protein/ Drosophila disc large tumor suppressor/ zonula occludens-1 protein domain of Dishevelled, a scaffolding protein required for the stabilization of the transcriptional co-activator beta-catenin. In addition, the CXXC domain of this protein has been shown to bind unmethylated CpG dinucleotides, localize to promoters and CpG islands, and interact with the catalytic domain of methylcytosine dioxygenase ten-eleven-translocation 2, an iron and alpha-ketoglutarate-dependent dioxygenase that modifies the methylation status of DNA. In humans, a mutation in this gene has been associated with development of malignant renal cell carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]

Database

Gene ID: 80319 CXXC4

Research Area

DATA IMAGES

GTX88280 IHC-P Image

IHC-P analysis of human breast using GTX88280 CXXC4 antibody, C-term.
Antigen retrieval : citrate buffer pH 6
Dilution : 3.8μg/ml

REFERENCE

There are currently no references for CXXC4 antibody, C-term (GTX88280). Be the first to share your publications with this product.

Submit a Reference

REVIEW

There are currently no reviews for CXXC4 antibody, C-term (GTX88280). Be the first to share your experience with this product.

Submit a Review

SDS
Sodium Azide.pdf

Package

List Price ($)

100 μg

$ 399

Qty