APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 1:500 - 1:1000 |
| 1:50 - 1:100 |
Not tested in other applications.
Calculated MW
PROPERTIES
Form
Liquid
Buffer
PBS, 50% Glycerol
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 160-340 of human CYP2B6 (NP_000758.1).
Purification
Purified by affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
cytochrome P450 family 2 subfamily B member 6 , CPB6 , CYP2B , CYP2B7 , CYP2B7P , CYPIIB6 , EFVM , IIB1 , P450
Background
This gene, CYP2B6, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize some xenobiotics, such as the anti-cancer drugs cyclophosphamide and ifosphamide. Transcript variants for this gene have been described; however, it has not been resolved whether these transcripts are in fact produced by this gene or by a closely related pseudogene, CYP2B7. Both the gene and the pseudogene are located in the middle of a CYP2A pseudogene found in a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
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GTX64899 IHC-P Image
IHC-P analysis of human breast cancer tissue using GTX64899 CYP2B6 antibody.
Dilution : 1:100
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GTX64899 IHC-P Image
IHC-P analysis of human colon tissue using GTX64899 CYP2B6 antibody.
Dilution : 1:100
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GTX64899 WB Image
WB analysis of various sample lysates using GTX64899 CYP2B6 antibody. The signal was developed with ECL plus-Enhanced.
Dilution : 1:1000
Loading : 25μg per lane
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GTX64899 IHC-P Image
IHC-P analysis of mouse lung tissue using GTX64899 CYP2B6 antibody.
Dilution : 1:100
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REFERENCE
There are currently no references for CYP2B6 antibody (GTX64899). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for CYP2B6 antibody (GTX64899). Be the first to share your experience with this product.
