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Calpastatin antibody [CSL1-5]

Cat. No. GTX12217

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 CSL1-5

Isotype

 IgG1

Application

 WB, IHC-Fr, ELISA

Reactivity

 Human
Package
50 μg ($399)
See all Calpastatin products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1-10 μg/ml
IHC-Fr 1-10μg/ml
ELISA 1-10μg/ml
Not tested in other applications.

Calculated MW

77 kDa. ( Note )

Product Note

This antibody specifically recognizes an epitope within domain III of human calpastatin.

PROPERTIES

Form

Liquid

Buffer

10mM PBS pH7.4, 1% BSA

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant human muscle- type calpastatin.

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

BS17 , CAST , PLACK , calpastatin , Calpastatin

Background

The protein encoded by this gene is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. It consists of an N-terminal domain L and four repetitive calpain-inhibition domains (domains 1-4), and it is involved in the proteolysis of amyloid precursor protein. The calpain/calpastatin system is involved in numerous membrane fusion events, such as neural vesicle exocytosis and platelet and red-cell aggregation. The encoded protein is also thought to affect the expression levels of genes encoding structural or regulatory proteins. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jun 2010]

Database

Research Area

REFERENCE

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REVIEW

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SDS
PBS.pdf
Package List Price ($)
$ 399