GeneTex
United States (US)

Caspase 9 (proform) recombinant protein

Cat No. GTX65493

Application ELISA, Functional Assay, Apuri, Blocking
Reactivity Human
Species Human
PROPERTIES

Form

Lyophilized powder

Buffer

free-dried powder from 50 mM Tris-HCl buffer, pH 8.0

Storage

This protein can be reconstituted in sterile water to 0.1-1.0 mg/ml after centrifugation. For long-term storage, a carrier protein (example 0.1% BSA) can be added. Store at -70ºC. Product is stable for at least 6-12 months.

Antigen Species

Human

Region/Sequence

The sequence corresponding to a region within amino acids 2 and 416 of human caspase9.

Expression System

E. coli

Purification


Purity was assessed by SDS-PAGE (≥90%) and by HPLC.

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

APAF-3, APAF3, CASPASE-9c, ICE-LAP6, MCH6, APAF 3, ICE LAP6, CASPASE 9c, Caspase 9 Proform, ICELAP6, CASPASE9c, Caspase9 Proform

Background

Caspase-9 is a member of the caspase family of cysteine proteases. Caspase-9 exists in cells as an inactive proenzyme. Proteolytic processing of this inactive proenzyme generates the large and small subunits which, when assembled as a tetramer (a pair of heterodimers), form the active caspase. Cascades of caspase activation have been shown to be the key signal-transducing events in apoptosis. Caspase-9 is considered to be an upstream enzyme that initiates caspase cascade leading to apoptosis.

Research Area

Package List Price ($)
$ 429