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Collagen VII antibody [LH7.2]

Cat. No. GTX26312

Reference 1

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 LH7.2

Isotype

 IgG1

Application

 WB, ICC/IF, IHC-P, IHC-Fr, Dot, ELISA

Reactivity

 Human, Goat, Sheep, Bovine, Guinea pig, Pig, Monkey, Marmoset
Package
100 μl ($399)
See all Collagen VII products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
ICC/IF Assay dependent
IHC-P Assay dependent
IHC-Fr 1:1,000
Dot Assay dependent
ELISA Assay dependent
Not tested in other applications.

Calculated MW

295 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Ascites

Preservative

15mM Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

insoluble fractions of neonatal human foreskin epidermal cells

Purification

Unpurified

Conjugation

Unconjugated

RRID

AB_385207

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

collagen type VII alpha 1 chain , EBD1 , EBDCT , EBR1 , NDNC8

Background

This gene encodes the alpha chain of type VII collagen. The type VII collagen fibril, composed of three identical alpha collagen chains, is restricted to the basement zone beneath stratified squamous epithelia. It functions as an anchoring fibril between the external epithelia and the underlying stroma. Mutations in this gene are associated with all forms of dystrophic epidermolysis bullosa. In the absence of mutations, however, an acquired form of this disease can result from an autoimmune response made to type VII collagen. [provided by RefSeq]

Database

Research Area

REFERENCE

Application Reference

Monniaux D et al. Cell Mol Life Sci 2019; Prenatal programming by testosterone of follicular theca cell functions in ovary.
Application : IHC-P
Reactivity : Sheep
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REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 399