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Cyclin T1 antibody

Anti-Cyclin T1 antibody used in Western Blot (WB). GTX17200
Anti-Cyclin T1 antibody used in IHC (Paraffin sections) (IHC-P). GTX17200
Anti-Cyclin T1 antibody used in IHC (Paraffin sections) (IHC-P). GTX17200

Cat. No. GTX17200

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, ELISA

Reactivity

 Human, Mouse, Rat
Package
100 μg ($399)
See all Cyclin T1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
IHC-P Assay dependent
ELISA Assay dependent
Not tested in other applications.

Calculated MW

81 kDa. ( Note )

Positive Control

Rat Brain Tissue Lysate(GTX27942)

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Rabbit polyclonal CCNT1 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human CCNT1.The immunogen is located within the last 50 amino acids of CCNT1.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

cyclin T1 , CCNT , CYCT1 , HIVE1

Cellular Localization

Nucleus

Background

This gene encodes a member of the highly conserved cyclin C subfamily. The encoded protein tightly associates with cyclin-dependent kinase 9, and is a major subunit of positive transcription elongation factor b (p-TEFb). In humans, there are multiple forms of positive transcription elongation factor b, which may include one of several different cyclins along with cyclin-dependent kinase 9. The complex containing the encoded cyclin and cyclin-dependent kinase 9 acts as a cofactor of human immunodeficiency virus type 1 (HIV-1) Tat protein, and is both necessary and sufficient for full activation of viral transcription. This cyclin and its kinase partner are also involved in triggering transcript elongation through phosphorylation of the carboxy-terminal domain of the largest RNA polymerase II subunit. Overexpression of this gene is implicated in tumor growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2013]

Database

Research Area

DATA IMAGES

Anti-Cyclin T1 antibody used in Western Blot (WB). GTX17200

GTX17200 WB Image

WB analysis of rat brain tissue using GTX17200 Cyclin T1 antibody in (A) the absence and (B) the presence of blocking peptide.
Dilution : 1 μg/ml

Anti-Cyclin T1 antibody used in IHC (Paraffin sections) (IHC-P). GTX17200

GTX17200 IHC-P Image

IHC-P analysis of rat brain tissue using GTX17200 Cyclin T1 antibody.
Dilution : 2.5 μg/ml

Anti-Cyclin T1 antibody used in IHC (Paraffin sections) (IHC-P). GTX17200

GTX17200 IHC-P Image

IHC-P analysis of rat brain tissue using GTX17200 Cyclin T1 antibody.
Working concentration : 20 μg/ml

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399