GeneTex
United States (US)

Cytokeratin Type II antibody [AE3]

Cytokeratin-Type-II-antibody-AE3-GTX16111-IHC-p-1_18121409_112.jpg

Cat No. GTX16111

Host Mouse
Clonality Monoclonal
Clone Name AE3
Isotype IgG1
Application WB, IHC-P, EM
Reactivity Human
APPLICATION

Application Note

Recommended Starting Dilutions:
For WB: Use at 1:1000-1:3000
Optimal dilutions should be determined experimentally by the researcher.

Specificity/Sensitivity

All basic (type II) human keratins K1, K2, K3, K4, K5, K6, K7, K8
PROPERTIES

Form

Liquid

Buffer

PBS + 0.1% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Human epidermal keratins

Purification

Protein G purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Background

The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is expressed largely in the upper spinous layer of epidermal keratinocytes and mutations in this gene have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq]
DATA IMAGES
Cytokeratin-Type-II-antibody-AE3-GTX16111-IHC-p-1_18121409_112.jpg

GTX16111 IHC-P Image

Immunohistochemical analysis of paraffin embedded human kidney with cytokeratin type II antibody [AE3]

Package List Price ($)
$ 319