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basic Cytokeratin antibody [AE3]

Anti-basic Cytokeratin antibody [AE3] used in IHC (Paraffin sections) (IHC-P). GTX16111

Cat. No. GTX16111

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 AE3

Isotype

 IgG1

Application

 WB, IHC-P, EM

Reactivity

 Human
Package
100 μl ($339)
See all basic Cytokeratin products

APPLICATION

Application Note

Recommended Starting Dilutions:
For WB: Use at 1:1000-1:3000
Optimal dilutions should be determined experimentally by the researcher.

Product Note

All basic (type II) human keratins K1, K2, K3, K4, K5, K6, K7, K8

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.1% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Human epidermal keratins

Purification

Protein G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Background

The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is expressed largely in the upper spinous layer of epidermal keratinocytes and mutations in this gene have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq]

Research Area

DATA IMAGES

Anti-basic Cytokeratin antibody [AE3] used in IHC (Paraffin sections) (IHC-P). GTX16111

GTX16111 IHC-P Image

Immunohistochemical analysis of paraffin embedded human kidney with cytokeratin type II antibody [AE3]

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 339