GeneTex
United States (US)

DNA Binding Protein-7 (DBP-7) recombinant protein

DNA-Binding-Protein-7-DBP-7-recombinant-protein_WB_GTX65431-1_18121410_218.jpg

Cat No. GTX65431

Application WB, ELISA, Functional Assay, Apuri, Blocking
Reactivity Human
Species Human
APPLICATION

Calculated MW

9.44 kDa. ( Note )
PROPERTIES

Form

Lyophilized powder

Storage

Reconstitute in ddH2O. Store at -20ºC.

Antigen Species

Human

Expression System

E. coli

Purification


Purity was assessed by SDS-PAGE (≥99%) and by HPLC.

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Chromodomain Helicase Dna Binding Protein 7,Crg,Hh5,Is3,Kal5,Chd7

Background

DNA Binding Protein-7 (DBP-7) is a N-terminal His-tagged recombinant protein and a member of the Sso7d family of small, abundant, non-specific DNA-binding proteins from the hyperthermophilic Archea Sulfolobus. The 7-kDa protein from Sulfolobus spp. consists of a five stranded, incomplete beta-barrel capped at the opening by a C-terminal alpha -helix; they bind to the minor groove of a DNA duplex via the triple-stranded beta-sheet. The topology of the Sulfolobus 7-kDa proteins was found to be similar to that of chromatin organization modifier (chromo) domains and eukaryotic SH3 domains, which are involved in protein–protein interactions. in vitro studies have shown that DBP-7 promotes the annealing of complementary DNA strands, induces negative supercoiling and chaperones the disassembly and renaturation of protein aggregates in an ATP hydrolysis-dependent manner.

Research Area

DATA IMAGES
DNA-Binding-Protein-7-DBP-7-recombinant-protein_WB_GTX65431-1_18121410_218.jpg

GTX65431 WB Image

Purity of recombinant DNA binding Protein -7 (2 µg) was analyzed by reduced SDS-PAGE electrophoresis

Package List Price ($)
$ 249