GeneTex

  • Country / Location Selection

United States (US)

Daxx antibody [DAXX-03]

Anti-Daxx antibody [DAXX-03] used in Western Blot (WB). GTX80185

Cat. No. GTX80185

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 DAXX-03

Isotype

 IgG1

Application

 WB, ICC/IF, IP

Reactivity

 Human
Package
100 μg ($399)
See all Daxx products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
ICC/IF Assay dependent
IP Assay dependent
Not tested in other applications.

Calculated MW

81 kDa. ( Note )

Product Note

This antibody reacts with C-terminal part of Daxx, a 110 kDa intracellular protein.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

15mM Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

His6-tagged protein corresponding to amino acids 580-740 of human Daxx.

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

BING2 , DAP6 , DAXX , EAP1 , death domain associated protein

Cellular Localization

Cytoplasm,Nucleus,Nucleoplasm,PML body,Nucleolus,Chromosome,Centromere

Background

This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2008]

Database

Research Area

DATA IMAGES

Anti-Daxx antibody [DAXX-03] used in Western Blot (WB). GTX80185

GTX80185 WB Image

WB analysis of U937 cell lysate using GTX80185 Daxx antibody [DAXX-03].

REFERENCE

There are currently no references for Daxx antibody [DAXX-03] (GTX80185). Be the first to share your publications with this product.
Submit a Reference

REVIEW

There are currently no reviews for Daxx antibody [DAXX-03] (GTX80185). Be the first to share your experience with this product.
Submit a Review
SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399